Sickle Cell Anemia - Form III Heterozygote Advantage?
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Answer the questions as best you can. The boxes will expand as you type if you need more space.
(Don't worry if it is a one word answer. The box size is standard.)
Read the following pages
Read and try and answer the questions at
(Note-you can "cheat" and have it fill in the mathematical
answers-let's face it, we haven't done Hardy-Weinberg yet!)
Question 1: Given what you
know about evolution, how can a deleterious gene, such as the one for sickle
cell anemia remain in a population at such a high level?
Question 2: Imagine you took a large population of Africans from the malaria
zone and moved them to an area without malaria. What would you imagine would
happen to the frequency of the gene for sickle cell anemia in the absence of
practice this was done by the institution of slavery. However, some slaves were
kept in tropical and sub-tropical areas that still experienced malaria, while
others were taken to areas free of the parasite. Remember slavery was not only a
US institution, but was common in the Caribbean and Central and South America.
After slavery the former slaves moved, in many cases north, away from the
malaria zones. Discuss how these migrations, both forced and voluntary, may have
effected the frequency of the gene for sickle cell anemia in North and South