Sickle Cell Anemia - Form I What causes it?
When you click Submit (at the bottom of this web page) it will save your
work on the server for me.
DO NOT Click submit more than once!
TAB OR USE THE MOUSE Between the
You are encouraged to work in small groups (pairs or
threes). You will only have to submit one paper per group (with all the names!)
Answer the questions as best you can. The boxes will expand as you type if you need more space.
(Don't worry if it is a one word answer. The box size is standard.)
At the Your Genes Your Health Site open the page on sickle
cell anemia (http://www.yourgenesyourhealth.org/sickle/whatisit.htm)
After reading the central portion with its summaries click on the tab to the
left that says "What Causes it?"
Read the section, answering the questions below as you go.
Question 1: If
you are African-American what is the likelihood you were born with Sickle Cell
Disease? Would the odd be higher or lower in Africa? Would it matter where in
Africa (I mean, Africa is a big place!) Why?
Question 2: What
chromosome contains the Beta Globin Gene? Where on the chromosome would
you find the gene (relative to the centromere)? What is wrong (VERY WRONG) with
the beautiful animation of transcription/translation?
Question 3: Describe how oxygen
affects the sickling process?
Question 4: What organs and
systems are most susceptible to problems due to sickle cells?