When you click Submit (at the bottom of this web page) it will
save your work on the server for me. If you get a "proxy error" hit
-refresh- until you get a "Thanks"
You might want to actually write your answers in Word (so you can
spell check them) and then cut-and-paste into the boxes. That way, if
the computer misplaces your work you can just re-paste the answers.
Since you may work on this over more than one day, and you can
at home, I will keep track of what
you have done. Feel free to click submit as you work to save your work
TAB OR USE THE MOUSE Between the
Answer the questions as best you can. The boxes will expand as you
type if you need more space. (Don't worry if it is a one word answer.
The box size is standard.)
Since you will be working in groups, put all the names of the
people in the
group in the box. The ideal group size is 2. As an exception I will
allow groups of 3. No groups of 4 or 5. If you work as a group of 3 I
expect better answers. Group sizes above 3 will be penalized in the
.In 2001 3 men won the Nobel Prize in Physiology based on their
work on the regulation of the cell cycle. Go to the page linked below
and follow the link in the right hand column that says "Illustrated
Go through the explanations and the game, answering my questions.
Question 1: Why do you think all three men work at research
centers where the study of cancer is the focus?
Question 2: In the "Introduction" the text says "CDK and cyclin
drive the cell..." What is meant by the term "drive" in this context?
Question 3: What controls the transition from G2 to M?
Question 4: When (in the section on Paul Nurse) it says "...the
CDK fuction has been conserved through evolution." what does it mean?
Remember, the boxes will expand as you type if you need more space.
Question 6: What happens to the level of cyclins during
Play the "Control
of the Cell Cycle Game" (you can use the link here or at the bottom
of the Nobel site's web pages).
Question 7: While the game loads you
can click on the cells and they do something. How many pairs of
chromosomes does this simulated cell have?
Question 8: In the "game" what does the first checkpoint
Question 10: What does the third checkpoint check for?